I am able to apply for Czech citizenship as I have been in the country for more than 5 years. I now have to pass some language exams and interviews. I hope that the fact that my grandmother is Czech will help.
Will help with the language, or with the bureacracy? I'd be surprised about the latter, but I'd also be surprised if they gave much trouble to an educated productive individual. Hodně štěstí!
My grandmother is from Prague. I didn't actually "decide" to move here. My mother offered me a house that she was to inherit in return for comming to take care of an eldery aunt. It was a deal that I couldn't refuse...